Etoposide Incorporated into Camel Milk Phospholipids Liposomes Shows Increased Activity against Fibrosarcoma in a Mouse Model

<div>Effects of various formulations of etoposide on benzo(a)pyrene- (BAP-) induced tumors in a mouse model. Treatment of tumor-bearing animals was started when the tumor size reached a volume of approximately 200 mm<sup>3</sup>. Mice treated with ETP-DPPC-liposomes or ETP-Cam-liposomes showed delayed tumor growth (<i>P</i> &lt; 0.05) as compared with controls (PBS and Sham liposomes). Treatment with ETP-DPPC-liposomes or ETP-Cam-liposomes was superior to free ETP (<i>P</i> &lt; 0.001). Data are values ± SD (<i>n</i> = 10 at initiation of therapy; the number varies at later time points due to mortality).</div>

BioMed Research International

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Figure 6

Figure 6: Etoposide Incorporated into Camel Milk Phospholipids Liposomes Shows Increased Activity against Fibrosarcoma in a Mouse Model 