Identification of Novel Breast Cancer Subtype-Specific Biomarkers by Integrating Genomics Analysis of DNA Copy Number Aberrations and miRNA-mRNA Dual Expression Profiling

Table 2

The topological properties of Bayesian networks for four gene groups.

Groups	Avg. degree	Avg. betweenness	Avg. clustering coefficient	Avg. closeness	Avg. number of neighbors	Network density	Network centralization	Characteristic path length	Network diameter	miRNA with highest degree in the network
Luminal-A gain	3.5	38.65	0.073	0.342	3.5	0.090	0.121	2.982	6	miR-26b
Luminal-A loss	2.9	63.24	0.185	0.125	2.9	0.054	0.136	3.724	9	miR-145
Basal-like gain	2.0	48.96	0.080	0.057	2.0	0.037	0.077	4.229	11	let-7e
Basal-like loss	2.4	35.98	0.088	0.039	2.4	0.046	0.092	3.943	11	miR-21