Review Article

The Association between Endometriomas and Ovarian Cancer: Preventive Effect of Inhibiting Ovulation and Menstruation during Reproductive Life

Figure 5

Molecular pathways involved in endometriosis-associated ovarian cancer pathogenesis from endometriotic lesions. In particular, activation of oncogenic KRAS and PI3K pathways and inactivation of tumor suppressor genes PTEN and ARID1A.