Novel Model of Pulmonary Artery Banding Leading to Right Heart Failure in Rats

Table 1

Ultrasound findings in the sham rats, at 4th or 8th week after the PAB procedure.

	Preoperative day			4th week			8th week
	Sham	PAL	PAC	Sham	PAL	PAC	Sham	PAL	PAC
	12	28	28	12	16	22	6	8	6
LVDd (mm)	4.66 ± 0.43	4.75 ± 0.43	4.67 ± 0.39	5.36 ± 0.36	5.10 ± 0.42	5.07 ± 0.51	5.78 ± 0.19	5.40 ± 0.29	5.42 ± 0.38
LVDs (mm)	2.10 ± 0.5	2.15 ± 0.47	2.06 ± 0.47	2.51 ± 0.38	2.88 ± 0.58	2.55 ± 0.31	2.90 ± 0.52	2.38 ± 0.38	2.68 ± 0.45
IVST (mm)	1.06 ± 0.27	1.11 ± 0.29	1.14 ± 0.31	1.57 ± 0.10	1.56 ± 0.16	1.65 ± 0.27	1.93 ± 0.21	1.90 ± 0.10	2.13 ± 0.22
PWT (mm)	1.01 ± 0.24	1.05 ± 0.27	1.04 ± 0.27	1.71 ± 0.29	1.51 ± 0.08	1.62 ± 0.20	2.23 ± 0.22	2.04 ± 0.09	1.97 ± 0.14
FS (%)	55.17 ± 8.74	55.02 ± 8.17	56.15 ± 8.68	53.27 ± 4.42	42.81 ± 15.09	49.78 ± 4.02	49.62 ± 10.14	56.07 ± 5.10	50.64 ± 5.51
RVDd (mm)	2.46 ± 0.31	2.49 ± 0.29	2.49 ± 0.26	2.43 ± 0.28	5.48 ± 1.47^∗	6.26 ± 1.28^∗	2.80 ± 0.58	5.26 ± 0.96^∗	6.95 ± 0.63^∗
RVWT (mm)	0.63 ± 0.19	0.65 ± 0.18	0.70 ± 0.17	0.54 ± 0.08	1.25 ± 0.11^∗	1.41 ± 0.28^∗	0.98 ± 0.1	1.72 ± 0.15^∗	1.80 ± 0.43^∗
TAPSE (mm)	2.71 ± 0.22	2.69 ± 0.21	2.69 ± 0.23	2.53 ± 0.14	2.40 ± 0.11	1.67 ± 0.20^∗	2.58 ± 0.1	2.32 ± 0.20	1.42 ± 0.25^∗
HR (bpm)	438 ± 43	441 ± 39	455 ± 24	447 ± 21	436 ± 26	422 ± 31	451 ± 22	419 ± 20	411 ± 30
Peak PAV (m/s)	0.76 ± 0.11	0.73 ± 0.12	0.71 ± 0.12	0.97 ± 0.14	2.93 ± 0.54^∗	3.91 ± 0.38^∗	1.05 ± 0.13	3.28 ± 0.37^∗	4.03 ± 0.27^∗
RVOTD (mm)	1.99 ± 0.20	2.00 ± 0.24	1.97 ± 0.25	2.64 ± 0.17	2.98 ± 0.37^#	3.22 ± 0.50^∗	2.20 ± 0.16	2.78 ± 0.37^#	3.62 ± 0.16^∗
AoD (mm)	2.23 ± 0.25	2.25 ± 0.23	2.30 ± 0.21	2.80 ± 0.18	2.65 ± 0.11	2.55 ± 0.22^#	2.78 ± 0.05	2.44 ± 0.35	2.65 ± 0.10
RVDd/LVDd	0.53 ± 0.08	0.53 ± 0.07	0.53 ± 0.05	0.46 ± 0.07	1.08 ± 0.28^∗	1.25 ± 0.32^∗	0.48 ± 0.09	0.971 ± 0.15^∗	1.28 ± 0.08^∗
RVOTD/AoD	0.90 ± 0.16	0.90 ± 0.16	0.86 ± 0.15	0.95 ± 0.07	1.12 ± 0.14^#	1.27 ± 0.20^∗	0.79 ± 0.07	1.157 ± 0.21^#	1.37 ± 0.10^∗†
RVPW/LVPW	0.65 ± 0.23	0.65 ± 0.21	0.69 ± 0.20	0.32 ± 0.05	0.83 ± 0.08^∗	0.87 ± 0.15^∗	0.44 ± 0.06	0.844 ± 0.07^∗	0.92 ± 0.24^∗

, number of rats. #: versus sham, ∗: versus sham, †: versus PAL, and : versus PAL.