Research Article
Novel Model of Pulmonary Artery Banding Leading to Right Heart Failure in Rats
Table 2
Weight analysis at the 4th and 8th week after the PAB procedure.
(a) Weight analysis at the 4th week after the procedure |
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BW | HW/BW | RV/BW | RV/(LV + IVS) | | (g) | ratio (mg/g) | ratio (mg/g) | ratio |
| Sham | 435 ± 39 | 3.57 ± 0.16 | 0.56 ± 0.07 | 0.21 ± 0.02 | PAL | 403 ± 21 | 4.65 ± 0.17∗ | 1.40 ± 0.13∗ | 0.50 ± 0.04∗ | PAC | 398 ± 33 | 4.88 ± 0.17∗ | 1.39 ± 0.03∗ | 0.49 ± 0.04∗ |
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(b) Weight analysis at the 8th week after the procedure |
| | BW | HW/BW | RV/BW | RV/(LV + IVS) | | (g) | ratio (mg/g) | ratio (mg/g) | ratio |
| Sham | 508 ± 41 | 3.30 ± 0.23 | 0.48 ± 0.04 | 0.21 ± 0.01 | PAL | 505 ± 47 | 4.34 ± 0.30∗ | 1.27 ± 0.12∗ | 0.54 ± 0.02∗ | PAC | 450 ± 50 | 4.81 ± 0.32∗ | 1.40 ± 0.07∗ | 0.58 ± 0.03∗ |
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There was no significant difference between the PAL and PAC groups. BW: body weight at the sacrifice time, HW: heart weight, and ∗:
versus sham.
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