Review Article

Nanoparticle Probes for Structural and Functional Photoacoustic Molecular Tomography

Figure 2

Photoacoustic molecular tomography of deep-embedded targets based on CuS Qdot probes. The agarose gels that contained CuS Qdots were placed in the background of chicken breast muscle with different chicken breasts stacked. (a) showed the configuration of chicken breast muscle stacked. (b) Photograph of chicken breast muscle that had the targets with CuS Qdots of (1) 100 μg/mL (2 OD), (2) 50 μg/mL (1 OD), (3) 25 μg/mL (0.5 OD), (4) 12.5 μg/mL (0.25 OD), (5) 6.25 μg/mL (0.125 OD), (6) gel without contrast agent, and (7) two needle tips at the center and 11 o’clock position. The photoacoustic image was shown at the bottom low with a depth of (c) 25 mm and (d) 50 mm. Reproduced with permission from [22].