Understanding Transcription Factor Regulation by Integrating Gene Expression and DNase I Hypersensitive Sites

Table 1

Transcription factor’s contribution value (TFCV) and estimated TFs’ functional levels (TFL) of top 10 selected PWMs.

Index	ID	TF name	PWM description	TFCV	TFL
1	M00772	IRF	Interferon regulatory factor family	326.928	14830.189
2	M01882	IRF-2	Interferon regulatory factor 2	325.779	14680.555
3	M02771	IRF-9	Interferon regulatory factor 9	322.969	15127.858
4	M00258	ISGF-3	Interferon-stimulated response element	320.613	9914.496
5	M01881	IRF-1	Interferon regulatory factor 1	320.501	15363.707
6	M02767	IRF-3	Interferon regulatory factor 3	317.408	11305.011
7	M00699	ICSBP	Interferon consensus sequence-binding protein	314.717	7242.987
8	M00248	Oct-1	Octamer factor 1	313.642	6287.612
9	M01235	IPF1	Homeodomain-containing transactivator	310.253	6593.312
10	M01857	AP-2 alpha	Activating enhancer binding protein 2 alpha	309.403	−3725.557