Levonorgestrel Inhibits Human Endometrial Cell Proliferation through the Upregulation of Gap Junctional Intercellular Communication via the Nuclear Translocation of Ser255 Phosphorylated Cx43

Figure 3

Effects of LNG on the apoptosis of endometrial cells analyzed by propidium iodide (PI) staining and flow cytometry. HESCs (a) and HEGCs (b) were treated in the absence (control) or presence of 5 × 10⁻⁵ mol/L LNG for 24 hs, 48 hs, and 72 hs. The cell cycle was analyzed by PI staining and flow cytometry, with 2 × 10⁴ cells counted. The histogram represents the mean ± S.D. of the apoptosis rate for HESCs (c) and HEGCs (d) in 6 patients. ; there was a significant difference, compared to the control.

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