Regulation of Cell Cycle Regulators by SIRT1 Contributes to Resveratrol-Mediated Prevention of Pulmonary Arterial Hypertension

Figure 3

Resveratrol plays an antiremodeling effect in pulmonary arteries. (a) Hemodynamics examinations ( = 8–10). , , and versus normal control; , versus vehicle treatment group. (b) Pulmonary arteries muscularization degrees ( = 5-6). , versus control; and versus corresponding vehicle group. (c) Representative H&E staining photomicrographs. (d) Pulmonary arteries medial wall thickness ( = 5-6). , , and versus control; , , and versus vehicle treatment group.

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