Regulation of Cell Cycle Regulators by SIRT1 Contributes to Resveratrol-Mediated Prevention of Pulmonary Arterial Hypertension

Figure 4

Resveratrol increases SIRT1 and p21 protein levels in PAH rats . Bar graphs show densitometric analysis of western blotting. The densitometric quantification was normalized to GAPDH. Data are shown as means ± SEM for five independent experiments. , , and versus control; , , and versus vehicle treatment group on day 14 or 21.