Hearing Assessment after Treatment of Nasopharyngeal Carcinoma with CRT and IMRT Techniques

Table 2

Factors predicting the average air and bone conduction threshold deterioration at the 1- to 5-year follow-up after RT.

Variables	(= 182)	Air (dB); Mean ± SEM	value	Bone (dB); Mean ± SEM	value
Sex
Female	53	15.67 ± 3.02	0.556	9.05 ± 12.27	0.591
Male	129	17.64 ± 1.65		10.12 ± 12.05
Radiation modality
2D-3D CRT	75	24.00 ± 2.34	0.000	14.04 ± 1.54	0.000
IMRT	107	12.21 ± 1.71		6.85 ± 0.99
Age (years)
50	89	18.73 ± 2.30	0.267	10.55 ± 1.38	0.421
50	93	15.47 ± 1.81		9.10 ± 1.15
Treatment regimen
RT alone	89	19.93 ± 2.23	0.060	10.65 ± 1.23	0.359
Chemoradiotherapy	93	14.32 ± 1.86		9.58 ± 1.30
Radiation dose
72 Gy	35	10.24 ± 3.01	0.017	6.66 ± 1.65	0.026
72 Gy	147	18.69 ± 1.63		10.26 ± 1.03
Otitis media effusion
No	111	15.54 ± 1.81	0.019	8.09 ± 1.00	0.016
Yes	71	19.46 ± 2.43		12.50 ± 1.65

SEM = standard error of the mean; RT = radiotherapy; 2D-3D CRT = 2-dimensional-3-dimensional conformal radiotherapy; IMRT = intensity-modulated radiotherapy.