Research Article

The Place of Extensive Surgery in Locoregional Recurrence and Limited Metastatic Disease of Breast Cancer: Preliminary Results

Table 2

Patients’ and tumours’ characteristics at the time of recurrence.

Age
 (i) <50 2
 (ii) 5022

Premenopausal status2
Menopausal status22

Free interval between primary tumour and recurrence (months)
 (i) Median duration 129
 (ii) Range24–242

Histological subtypes (24 tumours analyzed)Grade
 (i) Infiltrating ductal carcinoma18 (i) Grade I: 0
 (ii) Infiltrating lobular carcinoma4 (ii) Grade II: 7
 (iii) Mixed2 (iii) Grade III: 17

Endocrine status
 (i) ER (+)22
 (ii) PR (+)20
 (iii) ER and PR (−)2

Node dissection (24 patients)
 (i) Axillary retropectoral dissection14
 (ii) Mediastinal intramammary chain dissection7
 (iii) Node dissection not performed3
 (iv) Bone resection (sternal and rips resection)
   (a) Yes7
   (b) No17

Margin
 (i) R021
 (ii) R1 2
 (iii) Stop surgery for unresectable lesion1
 (iv) Bone infiltration
   (a) Yes (bone and rips)7
   (b) No17

Staging of the disease
 (i) Breast MRI24
 (ii) Abdominal and chest wall CT-scan24
 (iii) PET-CT22/24
 (iv) MRI of bone narrow7

Morbidity of the surgery2 limited necroses of flaps