Paricalcitol Inhibits Aldosterone-Induced Proinflammatory Factors by Modulating Epidermal Growth Factor Receptor Pathway in Cultured Tubular Epithelial Cells

<div>Aldosterone-induced inflammatory responses: role of the ADAM-17/TGF-<i>α</i>/EGFR axis and modulation by paricalcitol. (a) Aldosterone activates the ADAM-17/TGF-<i>α</i>/EGFR axis to regulate proinflammatory factors. (b) Paricalcitol inhibits aldosterone-induced activation of ADAM-17/TGF-<i>α</i>/EGFR signalling pathway. MR: mineralocorticoid receptor; VDRA: vitamin D receptor activators.</div>

BioMed Research International

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Figure 10: Paricalcitol Inhibits Aldosterone-Induced Proinflammatory Factors by Modulating Epidermal Growth Factor Receptor Pathway in Cultured Tubular Epithelial Cells 

Figure 10 | Paricalcitol Inhibits Aldosterone-Induced Proinflammatory Factors by Modulating Epidermal Growth Factor Receptor Pathway in Cultured Tubular Epithelial Cells 