Increased Circulating Advanced Oxidation Protein Products and High-Sensitive Troponin T in Cirrhotic Patients with Chronic Hepatitis C: A Preliminary Report
Table 1
Clinical and biochemical characteristics of the study subjects.
Healthy controls
Noncirrhotic patients
Cirrhotic patients
()
40
32
88
Male : female ratio
23 : 17
7 : 25
53 : 35
Age (years)
55 (29–56)
56 (38–69)
56 (21–74)
Ascites (%)
—
—
53 (73)
Esophageal varices (%)
—
—
47 (53)
Albumin (g/L)
45 (36–57)
37 (29–49)
30 (16–45)
ALT (U/L)
24 (20–28)
28 (24–33)
47 (16–79)
AST (U/L)
27 (23–30)
41 (19–64)
79 (19–150)
Bilirubin (mg/dL)
0.7 (0.6–0.9)
0.92 (0.90–0.95)
1.6 (1.0–3.6)
γGT (U/L)
26 (25–28)
48 (41–56)
92 (78–106)
Creatinine (mg/dL)
0.8 (0.7–1.2)
0.96 (0.9–1.2)
1.2 (0.7–2.4)
Serum sodium (mmol/L)
140 (138–141)
136 (129–138)
130 (129–142)
Mean arterial blood pressure (mmg/Hg)
—
—
83 (76–93)
hs-TnT (ng/L)
—
5.6 (3.0–7.1)
7.9 (3.0–18.5)
AOPPs-albumin (μmol/g)
1.7 (0.8–2.7)
2.1 (0.9–3.0)
2.4 (1.3–5.2)
Continuous variables are expressed as median (interquartile range, IQR) and categorical variables as number (percentage). Statistical significance: ; versus healthy controls. ALT: alanine aminotransferase; AOPPs: advanced oxidation protein products; AST: aspartate aminotransferase; hs-TnT: high-sensitive troponin T; INR: international normalised ratio; γGT: gamma glutamyltransferase.
