Research Article

Extramedullary Manifestation in Multiple Myeloma Bears High Incidence of Poor Cytogenetic Aberration and Novel Agents Resistance

Table 2

Clinical and FISH data of MM patients with EMD at relapse stage.

14

Age (median) range in years58 (39–78)

Sex (male/female)11/3

Stage (Durie-Salmon)IIIA11
IIIB3

Stage (ISS)I4
II5
III5

MM typeIgG5
IgA6
IgM1
Light chain2

FISH resultdel(17p13)3
del(13q14)4
amp(1q21)4
Not available6

Involved sites Soft tissues8
Central nervous system4
Skin2
Liver2

Median time to EMR (month)16.5 (3–70)