Research Article
Extramedullary Manifestation in Multiple Myeloma Bears High Incidence of Poor Cytogenetic Aberration and Novel Agents Resistance
Table 2
Clinical and FISH data of MM patients with EMD at relapse stage.
| | | 14 |
| Age (median) range in years | | 58 (39–78) |
| Sex (male/female) | | 11/3 |
| Stage (Durie-Salmon) | IIIA | 11 | IIIB | 3 |
| Stage (ISS) | I | 4 | II | 5 | III | 5 |
| MM type | IgG | 5 | IgA | 6 | IgM | 1 | Light chain | 2 |
| FISH result | del(17p13) | 3 | del(13q14) | 4 | amp(1q21) | 4 | Not available | 6 |
| Involved sites | Soft tissues | 8 | Central nervous system | 4 | Skin | 2 | Liver | 2 |
| Median time to EMR (month) | | 16.5 (3–70) |
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