Significance of Neutrophil Gelatinase-Associated Lipocalin Level-to-Serum Creatinine Ratio for Assessing Severity of Inflammation in Patients with Renal Dysfunction

Table 3

Regression analysis of NGAL and NGAL/sCr ratios versus inflammatory parameters in patients with renal dysfunction.

Variables	NGAL/sCr ratio		NGAL
	Univariate	Multivariate	Univariate	Multivariate
hsCRP (mg/dL)	0.591 (<0.001)	0.526 (<0.001)	0.487 (<0.001)	0.453 (<0.001)
cESR (mm/h)	0.454 (<0.001)	0.362 (<0.001)	0.267 (0.029)	0.230 (0.227)
Neutrophil (×10^9/L)	0.392 (<0.001)	0.241 (0.132)	0.253 (0.038)	0.218 (0.254)
NLR	0.452 (<0.001)	0.428 (<0.001)	0.354 (<0.001)	0.327 (<0.001)

Correlations between inflammatory parameters and the levels of the NGAL/sCr ratio and NGAL are expressed as standard β (P value). Multivariate: adjusted for age, BMI, systolic BP, hemoglobin, and troponin-I. NGAL, neutrophil gelatinase-associated lipocalin; NGAL/sCr ratio, NGAL-to-serum creatinine ratio; hsCRP, high sensitivity C-reactive protein; cESR, corrected erythrocyte sedimentation rate; NLR, neutrophil-to-lymphocyte ratio.