Diffuse Calcifications Protect Carotid Plaques regardless of the Amount of Neoangiogenesis and Related Histological Complications

Figure 2

Immunohistochemical staining for CD34 (a), (c), and (e) and Nestin (b), (d), and (f) in an uncomplicated noncalcified plaque (a) and (b), a calcified plaque (c) and (d), and a complicated noncalcified plaque (e) and (f). Neoangiogenesis in uncomplicated plaques is generally Nestin-negative. The overall neoangiogenesis in calcified plaques (complicated or not) is generally lower (both CD34 and Nestin) than in complicated plaques. Magnification 20x.

(a)

(b)

(c)

(d)

(e)

(f)