BioMed Research International / 2015 / Article / Tab 5

Review Article

Comparison of Fine Needle Aspiration and Fine Needle Nonaspiration Cytology of Thyroid Nodules: A Meta-Analysis

Table 5

Performance of the four diagnostic studies.

StudyFNAC/FNNAC
Histopathological diagnosisTPFPFNTPPerformance in diagnosis Diagnostic criteria for malignancyNotes
Sensitivity (%) Specificity (%)

de Carvalho et al. 2009 [10]53/5214/1310/81/028/3193.3/100 73.7/79.5Suspicious or positiveExcluded ND
McElvanna et al. 2009 [19]41/488/811/181/121/2188.9/88.9 65.6/53.8Not specifiedExcluded inadequate cytology specimens
Schoedel et al. 2008 [21]14/164/40/02/48/1066.7/50 100/100 Suspicious or positiveExcluded I and ND
Tauro et al. 2012 [15]38/382/10/00/136/36100/50 100/100 Not specified

TP: true positive, TN: true negative, FP: false positive, and FN: false negative. Sensitivity (%) = TP/(TP + FN) 100%; specificity (%) = TN/(TN + FP) 100%. ND: nondiagnostic and I: indeterminate, including follicular lesion and atypical cells present.