Surgical Modification of the Murine Calvaria Osteolysis Model

Figure 2

Schematic illustration of surgical process of group 1 (paraclip) and group 2 (transsuture). (a) Posterior skin incision between ears. (b) Periosteum removal. (c) Surgical incision closed with skin clip. (d) Percutaneous injection of UHMWPE particles suspension, 2 mm posterior to the caudal side of incision. (e) Final look of modified model (paraclip). (f) Traditional incision directly above the frontal and parietal bone. (g) Periosteum removal. (h) Interrupted skin sutures without knotting. (i) Direct injection of UHMWPE particles suspension. (j) Final look of traditional model (transsuture) after suture knotting.