Effects of Surgical and Dietary Weight Loss Therapy for Obesity on Gut Microbiota Composition and Nutrient Absorption

Table 2

Fecal short-chain fatty acid concentrations (mmol/100 g dry weight) in the dietary (VLCD; ) and sleeve gastrectomy (LSG, ) intervention groups before intervention (month 0) and after 3 and 6 months.

	VLCD				LSG
	Month 0	Month 3	Month 6	P trend	Month 0	Month 3	Month 6	P trend
Acetate	20.3 ± 3.8	15.6 ± 2.5	29.6 ± 1.9	0.4041	10.3 ± 1.7	16.5 ± 4.3	14.2 ± 3.0	0.3909
Propionate	5.8 ± 1.2	3.5 ± 0.5	3.7 ± 0.5	0.0954	3.5 ± 0.7	3.7 ± 0.8	3.5 ± 0.7	0.9743
n-Butyrate	4.5 ± 1.0	2.5 ± 0.6	2.5 ± 0.5	0.1095	2.2 ± 0.4	2.2 ± 0.6	2.5 ± 1.5	0.9232
i-Butyrate	0.6 ± 0.1	0.5 ± 0.1	0.5 ± 0.1	0.3393	0.4 ± 0.1	0.4 ± 0.1	1.0 ± 0.4	0.1973
i-Valeriate	0.8 ± 0.1	0.7 ± 0.1	0.7 ± 0.1	0.8427	0.6 ± 0.1	0.6 ± 0.1	0.6 ± 0.1	0.8458
Caproate	0.2 ± 0.0	0.2 ± 0.0	0.2 ± 0.0	0.6400	0.2 ± 0.0	0.2 ± 0.0	0.2 ± 0.0	0.8547
Total SCFA	30.7 ± 5.9	22.4 ± 3.8	21.9 ± 2.7	0.2862	18.2 ± 2.6	23.7 ± 6.3	24.9 ± 5.3	0.6192

SCFA: short chain fatty acids.