Clinical Study

The Impact of Vitamin D3 Supplementation on Mechanisms of Cell Calcium Signaling in Chronic Kidney Disease

Figure 5

The effect of vitamin D3 supplementation on permeability of P2X7 pores. (a) Representative flow cytometry histograms of ethidium bromide entry into PBMCs of a CKD patient at basal conditions (white peak) and after a stimulation by BzATP (50 μmol/L) (grey peak). (b) The comparison of the ethidium bromide permeability under the basal conditions, in BzATP- (50 μmol/L) stimulated and AZ11645373- (50 nmol/L) inhibited PBMCs before and after vitamin D3 supplementation.