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BioMed Research International
Volume 2015, Article ID 808639, 5 pages
Clinical Study

Macular Development in Aggressive Posterior Retinopathy of Prematurity

1Kresge Eye Institute, Wayne State University, Detroit, MI, USA
2Associated Retinal Consultants, P.C., Royal Oak, MI, USA
3Associated Retinal Consultants, William Beaumont Hospital, 3535 W 13 Mile Road, No. 344, Royal Oak, MI 48073, USA

Received 2 August 2014; Accepted 13 October 2014

Academic Editor: Anand Vinekar

Copyright © 2015 Hemang K. Pandya et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To report anatomic outcomes after early and confluent laser photocoagulation of the entire avascular retina, including areas in close proximity to the fovea, in patients with APROP. We aspire to demonstrate fundoscopic evidence of transverse growth and macular development following laser treatment in APROP. Methods. Retrospective review of 6 eyes with APROP that underwent confluent laser photocoagulation of the entire avascular retina. Photographic fundoscopic imaging was performed using the RetCam to compare outcomes after treatment. Results. Mean birth weight and gestational age were 704.8 g and 24.33 weeks, respectively. There were 2 females and 1 male. The average time to laser was 9.3 weeks after birth, with the mean postmenstrual age of 34 weeks. Two eyes had zone 1 and 4 eyes had posterior zone 2 disease. Three eyes developed 4A detachments, which were successfully treated. All 6 eyes experienced transverse growth, with expansion of the posterior pole and anterior displacement of the laser treatment. Conclusion. Confluent photocoagulation of the entire avascular retina, regardless of foveal proximity, should be the mainstay for treating APROP. Examination should be conducted within 5–10 days to examine areas previously hidden by neovascularization to ensure prudent therapy. Macular development involves both transverse and anterior-posterior growth.