Analgesic Effect of Intra-Articular Injection of Temperature-Responsive Hydrogel Containing Bupivacaine on Osteoarthritic Pain in Rats

Figure 4

Analgesic effects of intra-articular T-gel on chronic arthritic pain in MIA-induced OA rats. (a) Weight load after hydrogel injection, (b) paw withdrawal threshold (PWT) after hydrogel injection, (c) weight load after T-gel injection, and (d) PWT after T-gel injection. Asterisks (T-gel 50 μL), number signs (T-gel 30 μL), and dagger signs (T-gel 20 μL) indicate a statistically significantly difference from the control group (, , and ).

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