Quercetin Increases Hepatic Homocysteine Remethylation and Transsulfuration in Rats Fed a Methionine-Enriched Diet

Figure 2

Hepatic BHMT mRNA expression and activity. BHMT, betaine-homocysteine methyltransferase; 0.5% Q, 0.5% quercetin supplemented group; 1.0% Met, 1.0% Met supplemented group; 1.0% Met/0.5% Q, 1.0% Met plus 0.5% quercetin supplemented group. (a) Effect of quercetin on hepatic BHMT mRNA expression in rats fed a Met-enriched diet for 6 weeks. The mRNA expression of BHMT was normalized to β-actin. (b) Effect of quercetin on hepatic BHMT activity in rats fed a Met-enriched diet for 6 weeks. Results are expressed as mean and standard deviation (). No significant difference was found among the four groups.

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