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BioMed Research International
Volume 2015, Article ID 818656, 8 pages
Research Article

Rheology as a Tool to Predict the Release of Alpha-Lipoic Acid from Emulsions Used for the Prevention of Skin Aging

1Faculdade de Ciências Farmacêuticas, UNESP - Univ Estadual Paulista, LaCos, Rodovia Araraquara Jau, Km 1, CEP 14800-850 Araraquara, SP, Brazil
2Centro Universitário de Araraquara (UNIARA), Rua Carlos Gomes 1338, 14801-340 Araraquara, SP, Brazil
3Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Faculty of Pharmacy, University of Lisbon, Avenida Prof. Gama Pinto, 1649-003 Lisbon, Portugal

Received 29 July 2015; Revised 26 October 2015; Accepted 3 November 2015

Academic Editor: Michael D. Coleman

Copyright © 2015 Vera Lucia Borges Isaac et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Considering that the permeation of cosmetic active substances through the skin depends on the release of these substances from the vehicle, it is possible to understand that the rheological features of a cosmetic emulsion could influence in the permeation through the skin and, obviously, in the cosmetic effect of this substance. This research compares two formulations with different rheological characteristics through its release rate of alpha lipoic acid (ALA).

  1. Supplementary Material