Role of Extracellular Vesicles in Hematological Malignancies

Figure 1

The bone marrow niche and the major constituents relevant to hematological cancer progression: extracellular vesicles (exosomes and microvesicles) are integral part of tumor microenvironment, contributing to the development of a suitable niche for hematological cancer development. Extracellular vesicles released by different cell types allow the bidirectional communication among cancer cells and normal host cells.