Association between ANKK1 (rs1800497) and LTA (rs909253) Genetic Variants and Risk of Schizophrenia

Table 2

Allele frequencies and genotype distributions of ANKK1 rs1800497 (T>C) and LTA rs909253 (A>G) polymorphisms among Egyptian participants (120 cases and 100 controls).

(a)

Allele	Cases	Controls	Odds ratio	( value)	95% CI
	(frequency)	(frequency)
rs1800497:
T (A1)	43 (0.18)	57 (0.29)	1.8	2.9 (0.009)	1.2–2.9
C (A2)	197 (0.82)	143 (0.72)
rs909253:
+252A	162 (0.68)	116 (0.58)	0.7	2.1 (0.04)	0.5–1.0
+252G	78 (0.33)	84 (0.42)

(b)

Genotype	(%)	(%)	( value)
rs1800497:
TT (A1A1)	0 (0.0)	12 (12.0)	15.3 (0.0005)
TC (A1A2)	43 (35.8)	33 (33.0)
CC (A2A2)	77 (64.2)	55 (55.0)
rs909253:
AA	64 (53.3)	32 (32.0)	13.7 (0.001)
AG	34 (28.4)	52 (52.0)
GG	22 (18.3)	16 (16.0)

CI: confidence interval.