Postoperative Bleeding Risk for Oral Surgery under Continued Clopidogrel Antiplatelet Therapy

Table 1

Clinical features and bleeding rates in control and antiplatelet groups.

Features and Parameters	Antiplatelet medication			Chi-test, -test (control versus mono-/dual therapy group)
Group	Control	Clopidogrel	Clopidogrel/Aspirin	Significance	Power
Number of cases	281	64	60
Postoperative bleeding
Case	2	1	2
Rate (95% confidence)	0.7% (0.2–2.6%)	1.6% (0.3–8.3%)	3.3% (0.9–11.3%)	0.46/0.14	0.18/0.45
Age (years)	60.7 ± 6.3	67.9 ± 14.6	64.0 ± 10.8	<0.00/<0.00	0.98/0.74
Male/female	129/152	35/29	44/16	0.21/0.00	0.24/0.98
Numbers of teeth	1.7 ± 1.8	1.5 ± 0.8	1.5 ± 1.1	0.32/0.38	0.39/0.30
Dose		75 mg/day	75 mg + 100 mg/day
Indication for antithrombotic medication
Apoplexy + TIA		6	7	0.15
Stent + bypass		16	28
Myocardial infarction + other heart disorders		12	13
Others		3	3
Unknown		27	9