In Vitro Inhibitory and Cytotoxic Activity of MFM 501, a Novel Codonopsinine Derivative, against Methicillin-Resistant Staphylococcus aureus Clinical Isolates

Table 2

MIC, MBC, and MBC/MIC values for MFM 501 against additional S. aureus isolates.

MRSA isolates	MIC (µg/mL)	MBC (µg/mL)	MBC/MIC ratio
N391, N829, N850, U949, UM3, UM9, UM10	31.3	500	16
UM13, HN1, UM3, UM10, UM13, UM14, HN3	31.3	500	16
HN5, HN6, HN12, A1, HS770, HS3175, HS3178	31.3	500	16
A2, A3, A4, A7, C1, C4, C8, ATCC 33591	31.3	500	16
HN4, HN7, HN8, A8, C5, D3	31.3	250	8
N441, N1406, HN13, A9, C9, D1	15.6	500	32
HN14, BAA-1556	15.6	250	16
D5	125	125	1
D2	125	250	2
ATCC 700699	250	500	2
MSSA isolates	MIC (µg/mL)	MBC (µg/mL)	MBC/MIC ratio
ATCC 25923, UM9, HN9, HN10, HN11	31.3	500	16
A5, A6, B6	31.3	500	16
HN8, B1, C6	31.3	250	8
ATCC 35556	15.6	250	16
UM6	62.5	500	8