Mosaicism of Mitochondrial Genetic Variation in Atherosclerotic Lesions of the Human Aorta
Table 3
Major mitochondrial genome mutations in different types of total atherosclerotic lesion of morphologically mapped aortas.
Mutations
Primary total atherosclerotic lesion
Lipofibrous plaques
Fibrous plaques
Correlation coefficient
Asymptomatic significance
Correlation coefficient
Asymptomatic significance
Correlation coefficient
Asymptomatic significance
652delG
0.093
0.146
0.308*
0.091*
0.323*
0.071*
652insG
−0.075
0.186
−0.095
0.125
−0.058
0.232
A1555G
−0.359**
0.048**
−0.401**
0.039**
−0.084
0.195
C3256T
0.368**
0.045**
0.407**
0.045**
0.352**
0.050**
T3336C
0.426**
0.034**
0.437**
0.025**
0.103
0.119
C5178A
0.365**
0.046**
0.439**
0.023**
0.356**
0.048**
G12315A
0.353**
0.050**
0.409**
0.041**
−0.367**
0.046**
G13513A
−0.423**
0.035**
−0.437**
0.021**
0.095
0.143
G14459A
0.403**
0.042**
0.463**
0.026**
0.073
0.191
G14846A
−0.107
0.117
−0.351**
0.050**
0.052
0.214
G15059A
0.405**
0.043**
0.471**
0.015**
0.062
0.203
Correlation of mutations with atherosclerotic lesions at level of significance; **significant correlation of mutations with atherosclerotic lesions ().
