Cosuppression of Sprouty and Sprouty-Related Negative Regulators of FGF Signalling in Prostate Cancer: A Working Hypothesis

Figure 2

Histology of prostates from 24-week-old wild-type (a), hemizygous (b, c), and homozygous (d, e) null Spry1 mice. Five μm thin sections were stained with haematoxylin and eosin and assessed for normal acinar architecture and pathologies of low grade prostatic intraepithelial neoplasia (LGPIN) and high grade prostatic intraepithelial neoplasia (HGPIN) according to the Bar Harbor Classification of Mouse Prostate Pathologies [31]. Scale bar = 50 μm.

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