Review Article
Deep Response in Multiple Myeloma: A Critical Review
Table 2
Proposed new definition for deep response in multiple myeloma.
| New proposal for deep response
| Level of detection
| Project PFS
|
| | Deep CR grade 3 CR3 | Nonclonal plasma cells below 10−3, highly sensitive techniques FCM or sequencing should be employed | >35–45 months
|
| | Deep CR grade 5 CR5 | Nonclonal plasma cells below 10−5, highly sensitive techniques FCM or sequencing should be employed | >80 months
|
|
|
PR, partial response; MC, monoclonal component; PC, plasma cell; CR complete response; SFLC, serum free light chain; BM, bone marrow.
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