Research Article
Association of Tag SNPs and Rare CNVs of the MIR155HG/miR-155 Gene with Epilepsy in the Chinese Han Population
Table 4
Frequency distributions of the 4 tag SNPs between the DRE cases and the controls.
| | | DRE cases (%) | Controls (%) | OR (95% CI) | value |
| | rs969885 C>T | | | | | | C/T | 119 (88.81)/15 (11.19) | 499 (86.33)/79 (13.67) | 0.79 (0.36–1.72) | 0.548 | | CC/CT/TT | 53 (79.10)/13 (19.40)/1 (1.49) | 214 (74.05)/71 (24.57)/4 (1.38) | | 0.536 | | CC/CT+TT | 53 (79.10)/14 (20.90) | 214 (74.05)/75 (25.95) | 0.85 (0.36–2.04) | 0.717 | | CC+CT/TT | 66 (98.51)/1 (1.49) | 285 (98.62)/4 (1.38) | 5.07 (0.35–73.13) | 0.233 | | rs12483428 T>C | | | | | | T/C | 106 (79.10)/28 (20.90) | 496 (85.81)/82 (14.19) | 1.27 (0.63–2.57) | 0.511 | | TT/TC/CC | 44 (65.67)/18 (26.87)/5 (7.46) | 213 (73.70)/70 (24.22)/6 (2.08) | | 0.516 | | TT/TC+CC | 44 (65.67)/23 (34.33) | 213 (73.70)/76 (26.30) | 1.29 (0.57–2.90) | 0.542 | | TT+TC/CC | 62 (92.54)/5 (7.46) | 283 (97.92)/6 (2.08) | 1.55 (0.16–14.83) | 0.705 | | rs987195 C>G | | | | | | C/G | 94 (70.15)/40 (29.85) | 332 (57.44)/246 (42.56) | 1.59 (0.92–2.75) | 0.097 | | CC/CG/GG | 34 (50.75)/26 (38.81)/7 (10.45) | 100 (34.60)/132 (45.67)/57 (19.72) | | 0.118 | | CC/CG+GG | 34 (50.75)/33 (49.25) | 100 (34.60)/189 (65.40) | 1.98 (1.92–4.28) | 0.081 | | CC+CG/GG | 60 (89.55)/7 (10.45) | 232 (80.28)/57 (19.72) | 1.48 (0.54–4.03) | 0.448 | | rs4817027 G>A | | | | | | G/A | 96 (71.64)/38 (28.36) | 455 (78.72)/123 (21.28) | 1.72 (0.91–3.24) | 0.094 | | GG/GA/AA | 34 (50.75)/28 (41.79)/5 (7.46) | 174 (60.21)/107 (37.02)/8 (2.77) | | 0.074 | | GG/GA+AA | 34 (50.75)/33 (49.25) | 174 (60.21)/115 (39.79) | 1.63 (0.76–3.52) | 0.213 | | GG+GA/AA | 62 (92.54)/5 (7.46) | 281 (97.23)/8 (2.77) | 13.13 (1.40–123.83) | 0.024 |
|
|
OR: odds ratio; 95% CI: 95% confidence interval. OR (95% CI) and values have been adjusted for gender and age in the logistic regression analyses.
|
