Nonalcoholic Fatty Liver Disease Relationship with Metabolic Syndrome in Class III Obesity Individuals

Table 4

Mean serum concentrations of biochemical indicators of liver function and damage according to the staging of NAFLD.

Variables	The staging of NAFLD by liver biopsy			Comparison of staging of NAFLD	value
	Steatosis ()	Steatohepatitis without fibrosis ()	Steatohepatitis with fibrosis ()
AP (U/L)	75.1 ± 24.9	78.3 ± 20.2	73.1 ± 1.4	Steatosis × steatohepatitis without fibrosis	0.809
				Steatosis × steatohepatitis with fibrosis	0.892
				Steatohepatitis without fibrosis × steatohepatitis with fibrosis	0.767
AST (U/L)	22.9 ± 12.8	29.9 ± 26.7	30.2 ± 7.6	Steatosis × steatohepatitis without fibrosis	0.195
				Steatosis × steatohepatitis with fibrosis	0.547
				Steatohepatitis without fibrosis × steatohepatitis with fibrosis	0.484
ALT (U/L)	27.1 ± 15.5	28.2 ± 17.5	28.9 ± 10.3	Steatosis × steatohepatitis without fibrosis	0.216
				Steatosis × steatohepatitis with fibrosis	0.330
				Steatohepatitis without fibrosis × steatohepatitis with fibrosis	0.242
GGT (U/L)	29.4 ± 17.8	42.6 ± 27.7	62.4 ± 14.6	Steatosis × steatohepatitis without fibrosis	0.104
				Steatosis × steatohepatitis with fibrosis	0.045
				Steatohepatitis without fibrosis × steatohepatitis with fibrosis	0.566
Alb (g/dL)	4.5 ± 0.7	3.9 ± 0.3	3.3 ± 0.2	Steatosis × steatohepatitis without fibrosis	0.236
				Steatosis × steatohepatitis with fibrosis	<0.001
				Steatohepatitis without fibrosis × steatohepatitis with fibrosis	0.003

Mean and standard deviation; Alb: albumin; ALT: alanine aminotransferase; AP: alkaline phosphatase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transpeptidase.