Research Article

Topical Anti-Inflammatory Effects of Isorhamnetin Glycosides Isolated from Opuntia ficus-indica

Table 2

Effect of Opuntia ficus-indica (OFI) extract, isorhamnetin, and its glycosides in RAW 264.7 cell viability.

TreatmentCell viability (%)
25 ng/mL#50 ng/mL125 ng/mL

Isorhamnetin99.3 ± 5.6a*97. 5 ± 5.3a97.7 ± 2.1a
IGP96.7 ± 2.4ab88.9 ± 5.3b84.9 ± 4.0cd
IGR92.2 ± 3.1b85.2 ± 5.1b81.6 ± 3.0d
IGRR99.4 ± 2.9a98.5 ± 2.3a95.7 ± 4.5ab
IGRP99.4 ± 3.9a97.5 ± 2.8a94.2 ± 4.0ab
OFI extract94.5 ± 1.2ab92.6 ± 4.8ab89.9 ± 1.9bc

#Concentration expressed in ng IsoEq/mL. IGP: isorhamnetin-glucosyl-pentoside; IGR: isorhamnetin-glucosyl-rhamnoside; IGRR: isorhamnetin-glucosyl-rhamnosyl-rhamnoside; IGRP: isorhamnetin-glucosyl-rhamnosyl-pentoside. *Different letters in each column denote significant differences among treatments ().