Spatially Enhanced Differential RNA Methylation Analysis from Affinity-Based Sequencing Data with Hidden Markov Model

Figure 5

Boxplot of AUCs for different thresholds applied to switch FDR to the binary state. This figure shows that with the variation of thresholds, the performance of FHB outperforms exomePeak in AUC on 100 datasets. exomePeak does not use the cut-off threshold so its performance remains the same. The performance is evaluated at bin level rather than peak level in all experiments.