Spatially Enhanced Differential RNA Methylation Analysis from Affinity-Based Sequencing Data with Hidden Markov Model

Figure 6

Boxplot of AUCs for different transition matrices used to generate the ground truth. The performance of FHB and FHC strategies heavily relies on the transition matrix setting, which reflects the degree of dependence between adjacent bins; and FHC strategy outperforms FHB and exomePeak under different settings tested.