Spatially Enhanced Differential RNA Methylation Analysis from Affinity-Based Sequencing Data with Hidden Markov Model

Figure 9

values of motifs identified from differential methylation regions. The figure shows the motif values from exomePeak and FastFHC strategy. With spatially enhanced differential methylation analysis, FastFHC identifies RNA methylation sites that are more biologically meaningful, indicating higher specificity compared with the exomePeak result.