Research Article

Clique-Based Clustering of Correlated SNPs in a Gene Can Improve Performance of Gene-Based Multi-Bin Linear Combination Test

Table 2

Mean and standard deviation over 1000 genes of agreement measure and for two clustering methods (LDSelect and CLQ) and number of genes with identical clustering.

Allele frequency cutCases of perfect agreement
MeanSDMeanSD

.05.3.6760.203.3250.342180
.4.7690.191.5100.336283
.5.8470.168.6650.303388
.6.9090.123.7810.242483
.7.9360.101.8320.210541
.8.9590.086.8840.178648
.9.9740.069.9180.156736

.01.3.6890.196.3950.376155
.4.7890.177.5590.379254
.5.8630.151.6870.338361
.6.9230.105.7940.267468
.7.9480.084.8430.230536
.8.9680.068.8920.201644
.9.9810.053.9220.172744