Environmental Lead Exposure, Catalase Gene, and Markers of Antioxidant and Oxidative Stress Relation to Hypertension: An Analysis Based on the EGAT Study

Table 1

General characteristics and biochemical parameters of study population according to hypertension.

Variables	Normotension; ( = 332)	Prehypertension; ( = 432)	Hypertension; ( = 222)
Age, yrs (AM ± SE)	51.58 ± 0.23	52.01 ± 0.20	52.96 ± 0.33
Age group, (%)
40–55 yrs	267 (80.4)	328 (75.9)	152 (68.5)
>55 yrs	65 (19.6)	104 (24.1)	70 (31.5)
BMI, kg/m^2 (AM ± SE)	23.58 ± 0.16	25.09 ± 0.15^a	26.26 ± 0.25^a
Drinking status, (%)
Nondrinkers	125 (37.7)	165 (38.2)	67 (30.2)
Drinkers	207 (62.3)	267 (61.8)	155 (69.8)
Smoking status, (%)
Nonsmokers	247 (74.4)	342 (79.2)	156 (70.3)
Smokers	85 (25.6)	90 (20.8)	66 (20.8)
Biochemical tests (AM ± SE)
Triglyceride, mg/dL	132.81 ± 4.04	165.78 ± 5.35^a	191.47 ± 8.81^a,b
HDL cholesterol, mg/dL	49.57 ± 0.57	48.74 ± 0.49	49.32 ± 0.071
LDL cholesterol, mg/dL	152.31 ± 2.14	148.49 ± 1.91	146.61 ± 2.72
Total cholesterol, mg/dL	228.55 ± 2.31	230.33 ± 2.09	233.02 ± 2.79
Fasting glucose, mg/dL	100.58 ± 1.35	105.91 ± 1.24^a	112.65 ± 3.09^a,b
Creatinine, mg/dL	1.10 ± 0.07	1.14 ± 0.01^a	1.14 ± 0.01^a
Uric acid, mg/dL	5.97 ± 0.06	6.40 ± 0.06^a	6.61 ± 0.08^a,b

Significantly different from normotension and prehypertension, respectively, .