Environmental Lead Exposure, Catalase Gene, and Markers of Antioxidant and Oxidative Stress Relation to Hypertension: An Analysis Based on the EGAT Study

Table 2

Blood lead level, antioxidants, and oxidative stress determinants of study population, according to hypertension.

Variables	Normotension; ( = 332)	Prehypertension; ( = 432)	Hypertension; ( = 222)
Blood lead, g/dL	4.41 ± 0.10	4.55 ± 0.09	5.28 ± 0.21^a,b
Antioxidant biomarkers
CAT, U/gHb	29966 ± 549	28543 ± 422	28084 ± 600
SOD, U/gHb	2417 ± 80	2365 ± 71	2363 ± 96
GPx, U/gHb	34.56 ± 0.85	34.92 ± 0.78	36.11 ± 1.14
GSH, mg/dL	31.42 ± 0.34	31.41 ± 0.32	31.34 ± 0.46
Oxidative stress biomarker
MDA, mol/L	8.23 ± 0.34	8.02 ± 0.26	9.64 ± 0.45^a,b

Significantly different from normotension and prehypertension, respectively, .