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BioMed Research International
Volume 2015 (2015), Article ID 857327, 9 pages
http://dx.doi.org/10.1155/2015/857327
Research Article

How to Choose In Vitro Systems to Predict In Vivo Drug Clearance: A System Pharmacology Perspective

1Bioinformatics Research Center, College of Automation, Harbin Engineering University, Harbin, Heilongjiang 150001, China
2Biomedical Engineering Institute, College of Automation, Harbin Engineering University, Harbin, Heilongjiang 150001, China
3Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University, Indianapolis, IN 46202, USA
4School of Informatics and Computing, Indiana University, Indianapolis, IN 46202, USA
5Pattern Recognition and Intelligent System Institute, College of Automation, Harbin Engineering University, Harbin, Heilongjiang 150001, China
6Department of Obstetrics and Gynecology, School of Medicine, Indiana University, Indianapolis, IN 46202, USA
7Department of Medical and Molecular Genomics, School of Medicine, Indiana University, Indianapolis, IN 46202, USA

Received 13 November 2014; Revised 23 January 2015; Accepted 4 February 2015

Academic Editor: Stelvio M. Bandiera

Copyright © 2015 Lei Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Lei Wang, ChienWei Chiang, Hong Liang, et al., “How to Choose In Vitro Systems to Predict In Vivo Drug Clearance: A System Pharmacology Perspective,” BioMed Research International, vol. 2015, Article ID 857327, 9 pages, 2015. doi:10.1155/2015/857327