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BioMed Research International
Volume 2015, Article ID 857628, 5 pages
http://dx.doi.org/10.1155/2015/857628
Research Article

Association of Aortic Diameters with Coronary Artery Disease Severity and Albumin Excretion

1Department of Cardiology, Uludağ University, Bursa, Turkey
2Şevket Yılmaz Government Research and Training Hospital, Bursa, Turkey
3Department of Public Health, Cumhuriyet University, Sivas, Turkey
4Tıp Fakültesi Kalp, Damar Cerrahisi Anabilim Dalı, Uludağ Üniversitesi, Görükle Kampüsü, Nilüfer, 16059 Bursa, Turkey

Received 17 February 2015; Revised 7 April 2015; Accepted 8 April 2015

Academic Editor: Juan A. Sanchis-Gimeno

Copyright © 2015 Bülent Özdemir et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Aortic diameters, aortic distensibility, microalbuminuria, coronary artery disease which are all together related to vascular aging are investigated in this paper. Methods. Eighty consecutive nondiabetic patients undergoing elective coronary angiography were enrolled into the study. Systolic and diastolic aortic diameters, aortic distensibility, CAD severity by angiogram with the use of Gensini scoring, and albumin excretion rates were determined. Results. Cases with CAD had significantly larger systolic (30,72 ± 3,21 mm versus 34,19 ± 4,03 mm for cases without and with CAD, resp.) and diastolic aortic diameters measured 3 cm above aortic valve compared to patients without CAD (33,56 ± 4,07 mm versus 29,75 ± 3,12 mm). The systolic and diastolic diameters were significantly higher in albuminuria positive patients compared to albuminuria negative patients (p = 0.017 and 0.008, resp., for systolic and diastolic diameters). Conclusion. In conclusion aortic diameters are increased in patients with coronary artery disease and in patients with microalbuminuria. In CAD patients, systolic blood pressure, pulse pressure, aortic systolic and diastolic pressure, and albumin excretion rate were higher and aortic distensibility was lower.