Variants of SCARB1 and VDR Involved in Complex Genetic Interactions May Be Implicated in the Genetic Susceptibility to Clear Cell Renal Cell Carcinoma

Table 1

Data for the studied 40 polymorphisms.

Locus	Gene	Chromosome	Position (GRCh38)	Allele variants	MAF	Reference
rs34796867	ZC3H12A	1	37475773	C/T	T = 0.000	[20]
rs113322875	ZC3H12A	1	37477383	G/A	A = 0.000	[20]
rs34031609	ZC3H12A	1	37482928	G/A	A = 0.000	[20]
rs113655247	ZC3H12A	1	37483276	G/C	C = 0.000	[20]
rs17849897	ZC3H12A	1	37483451	C/T	T = 0.014	[20]
rs12105918	ZEB2	2	144450626	G/A	G = 0.051	[10]
rs11894252	EPAS1	2	46306237	C/T	T = 0.356	[6]
rs7579899	EPAS1	2	46310465	C/T	T = 0.357	[6]
rs9679290	EPAS1	2	46330505	G/C	C = 0.451	[6]
rs4953346	EPAS1	2	46331069	C/A	C = 0.452	[6]
rs3834129	CASP8	2	201232809:14	CTTACT/—	Del = 0.450	[17]
rs833061	VEGFA	6	43769749	C/T	C = 0.484	[14]
rs748964	RXRA	9	134442243	G/C	G = 0.144	[13]
rs3118523	RXRA	9	134443675	G/A	G = 0.202	[13]
rs7105934	11q13.3	11	69424973	C/T	T = 0.040	[6]
rs1049380	ITPR2	12	26336611	G/T	G = 0.436	[9]
rs739837	VDR	12	47844438	C/A	A = 0.471	[13]
rs731236	VDR	12	47844974	G/A	G = 0.354	[13]
rs7975232	VDR	12	47845054	G/T	T = 0.469	[13]
rs1544410	VDR	12	47846052	C/T	T = 0.361	[13]
rs2228570	VDR	12	47879112	G/A	A = 0.456	[13]
rs2238136	VDR	12	47883930	G/A	A = 0.365	[13]
rs4516035	VDR	12	47906043	C/T	C = 0.458	[13]
rs7139166	VDR	12	47906551	G/C	G = 0.454	[13]
rs11568820	VDR	12	47908762	C/T	T = 0.128	[13]
rs4765623	SCARB1	12	124836304	G/A	A = 0.361	[6]
N29insA	MC1R	16	89919345	C/A	A = 0.000	[2]
rs1805005	MC1R	16	89919436	G/T	T = 0.078	[2]
rs1805006	MC1R	16	89919510	C/A	A = 0.001	[2]
rs2228479	MC1R	16	89919532	G/A	A = 0.108	[2]
rs11547464	MC1R	16	89919683	G/A	A = 0.007	[2]
rs1805007	MC1R	16	89919709	C/T	T = 0.040	[2]
Y152OCH	MC1R	16	89919714	C/A	A = 0.000	[2]
rs1110400	MC1R	16	89919722	C/T	C = 0.026	[2]
rs1805008	MC1R	16	89919736	C/T	T = 0.068	[2]
rs885479	MC1R	16	89919746	C/T	T = 0.035	[2]
rs1805009	MC1R	16	89920138	G/C	C = 0.001	[2]
rs9904341	BIRC5	17	78214286	G/C	C = 0.343	[15]
rs7121	GNAS1	20	58903752	C/T	T = 0.465	[12]
rs132770	XRCC6	22	41621260	G/A	A = 0.153	[16]

MAF = minor allele frequency.