Variants of SCARB1 and VDR Involved in Complex Genetic Interactions May Be Implicated in the Genetic Susceptibility to Clear Cell Renal Cell Carcinoma

Table 3

Interaction effects of statistical significance in ccRCC development revealed with binary logistic regression analysis.

Interacting loci	Genes	OR (95% CI) for interaction model	value for interaction model
rs4765623rs9679290	SCARB1EPAS1	1.371 (1.087–1.729)	0.008
rs7121rs9679290	GNAS1EPAS1	1.284 (1.047–1.575)	0.016
rs7121rs1805008	GNAS1MC1R	2.601 (1.089–6.212)	0.031
rs7121rs2228570	GNAS1VDR	1.240 (1.018–1.510)	0.032
MC1R “r”rs7975232	MC1RVDR	1.341 (1.020–1.763)	0.035
rs7121rs4765623	GNAS1SCARB1	1.639 (1.020–2.639)	0.041