Research Article
Variants of SCARB1 and VDR Involved in Complex Genetic Interactions May Be Implicated in the Genetic Susceptibility to Clear Cell Renal Cell Carcinoma
Table 4
Results of multivariate binary logistic regression analysis concerning all SNPs under study, haplotypes, and disclosed interactions.
| Multivariate binary logistic regression analysis | Variables in the model | Genes | OR (95% CI) | value of variable in the model |
| Haplotype CAGT (rs739837-rs731236-rs7975232-rs1544410) | VDR | cs | 0.005 | rs4765623rs9679290 | SCARB1EPAS1 | 1.389 (1.094–1.763) | 0.007 | MC1R “r”rs7975232 | MC1RVDR | 1.455 (1.095–1.933) | 0.010 | rs7121rs2228570 | GNAS1VDR | 1.238 (1.009–1.518) | 0.041 |
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