Shear Stress Induces Differentiation of Endothelial Lineage Cells to Protect Neonatal Brain from Hypoxic-Ischemic Injury through NRP1 and VEGFR2 Signaling

Figure 6

The immunofluorescence staining revealed the phosphorylation of VEGFR2 (a) and Akt (b) after application of ELCs in HI injured brain. The colocalization of p-Akt (red) with angiogenesis marker IB4 (green) indicated the involvement of Akt signaling in vascular regeneration. , Scale bar: 100 μm.

(a)

(b)