Clinical Study

Rebamipide Improves Chronic Inflammation in the Lesser Curvature of the Corpus after Helicobacter pylori Eradication: A Multicenter Study

Table 3

Comparison of histological gastritis before and after H. pylori eradication in the untreated group.

Before eradicationAfter eradication value

GC of the middle antrum Activity0.94 ± 0.11 (52)0.06 ± 0.02 (52)<0.0001
Inflammation2.31 ± 0.10 (52)1.37 ± 0.07 (52)<0.0001
Atrophy1.25 ± 0.07 (52)0.96 ± 0.10 (52)0.0098
Intestinal metaplasia0.73 ± 0.16 (52)0.44 ± 0.11 (52)0.0719

GC of the middle corpusActivity1.21 ± 0.10 (52)0.00 ± 0.00 (49)<0.0001
Inflammation2.35 ± 0.09 (52)1.29 ± 0.09 (49)<0.0001
Atrophy1.02 ± 0.09 (52)0.36 ± 0.08 (49)<0.0001
Intestinal metaplasia0.23 ± 0.08 (52)0.27 ± 0.09 (49)0.7988

LC of the middle corpus Activity0.94 ± 0.11 (48)0.00 ± 0.00 (49)<0.0001
Inflammation2.40 ± 0.10 (48)1.35 ± 0.08 (49)<0.0001
Atrophy1.08 ± 0.09 (48)0.80 ± 0.10 (49)0.0178
Intestinal metaplasia0.96 ± 0.17 (48)0.78 ± 0.16 (49)0.3537

Data are presented as mean ± standard error (). GC: greater curvature and LC: lesser curvature.