Evaluation of Influence of Various Polymers on Dissolution and Phase Behavior of Carbamazepine-Succinic Acid Cocrystal in Matrix Tablets

Table 2

Composition of different CBZ tablets formulations.

Composition of matrix tablet	Code	Drug : polymer	Percent drug released after six hours
CBZ: HPMC	CH-1	1 : 1.25	25 ± 2.3
	CH-2	1 : 0.625	36 ± 1.9
	CH-3	1 : 0.31	45 ± 2.5
CBZ: Soluplus	CS-1	1 : 1.25	83 ± 0.9
	CS-2	1 : 0.625	72 ± 1.9
	CS-3	1 : 0.31	67 ± 3.1
CBZ: Kollidon VA 64	CK-1	1 : 1.25	90 ± 2.6
	CK-2	1 : 0.625	59 ± 4.7
	CK-3	1 : 0.31	43 ± 4.1