Research Article
Evaluation of Influence of Various Polymers on Dissolution and Phase Behavior of Carbamazepine-Succinic Acid Cocrystal in Matrix Tablets
Table 3
Physical evaluation of cocrystal tablets.
| Formulation | Weight (mg) | Thickness (mm) | Hardness (N) | Diameter (mm) |
| CSH-1 | 497.31 ± 3.50 | 4.66 ± 0.01 | 210.34 ± 6.30 | 10.00 ± 0.01 | CSH-2 | 372.04 ± 1.52 | 4.20 ± 0.01 | 200.71 ± 5.12 | 10.01 ± 0.01 | CSH-3 | 309.67 ± 24 | 3.85 ± 0.01 | 197.56 ± 6.35 | 10.02 ± 0.01 | CSS-1 | 495.92 ± 4.50 | 4.56 ± 0.01 | 217.34 ± 5.18 | 10.01 ± 0.01 | CSS-2 | 374.39 ± 2.82 | 4.13 ± 0.01 | 205.67 ± 4.90 | 10.01 ± 0.00 | CSS-3 | 311.71 ± 1.39 | 3.77 ± 0.01 | 210.07 ± 7.37 | 10.02 ± 0.00 | CSK-1 | 499.19 ± 2.17 | 4.71 ± 0.01 | 197.01 ± 6.05 | 10.01 ± 0.00 | CSK-2 | 308.54 ± 3.13 | 4.18 ± 0.01 | 213.21 ± 3.57 | 10.00 ± 0.00 | CSH-3 | 307.76 ± 4.00 | 3.86 ± 0.01 | 208.78 ± 5.62 | 10.02 ± 0.01 |
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